Body mass index and two-year change of in vivo Alzheimer’s disease pathologies in cognitively normal older adults

Table 2 Association of the baseline BMI with neuroimaging biomarker changes for 2-year

	Estimate	95% CI	t value	p value
Dependent variable: Aβ deposition
Model 1^a
Baseline BMI x time	0.000	-0.003 to 0.002	-0.359	.720
Model 2^b
Baseline BMI x time	0.000	-0.003 to 0.002	-0.426	.671
Dependent variable: Tau deposition
Model 1^a
Baseline BMI x time	-0.018	-0.030 to -0.006	-3.027	.003
Model 2^b
Baseline BMI x time	-0.016	-0.028 to -0.004	-2.703	.008

Abbreviations: Aβ β-amyloid protein, BMI body mass index, CI confidence interval
^aAdjusted for age, sex, APOE4, baseline Aβ or Tau and their interactions with time
^bAdjusted for age, sex, APOE4, baseline Aβ a or Tau, vascular risk score, and their interactions with time

ISSN: 1758-9193