Table 1 Participant characteristics
Variable | Total | Tau PET |
|---|---|---|
No. of individuals | 194 | 45 |
Age at baseline, year (mean ± SD) | 68.4 ± 8.1 | 70.3 ± 7.3 |
Female, No. (%) | 102 (53) | 25 (55.6) |
Education, year, median (IQR) | 12 (7) | 12(4) |
APOE ε4 carriers, No. (%) | 35 (18.0) | 8 (17.8) |
Baseline BMI, kg/m2 (mean ± SD) | 24.20 ± 3.01 | 24.5 ± 2.55 |
Vascular risk factor, No. (%) | ||
Diabetes mellitus | 35 (18.0) | 10 (22.2) |
Hypertension | 87 (44.8) | 21 (46.7) |
Hyperlipidemia | 69 (35.6) | 15 (33.3) |
Coronary heart disease | 11 (5.7) | 3 (6.7) |
Stroke | 0 | 0 |
TIA | 1 (0.5) | 1 (2.2) |
VRS, median (IQR) | 1 (0–2) | 1 (0–2) |
Alcohol use, No. (%) | ||
Never | 98 (50.5) | 25(55.6) |
Former | 23 (11.9) | 7 (15.6) |
Drinker | 73 (37.6) | 13 (28.9) |
Smoking status, No. (%) | ||
Never | 125 (64.4) | 30 (66.7) |
Former | 57 (29.4) | 13 (28.9) |
Drinker | 12 (6.2) | 2 (4.4) |
Lifetime physical activity, MET, median (IQR) | 68.7 (57.2) | 64.5 (42.1) |
Cerebral Aβ deposition, SUVR | ||
Baseline global Aβ retention, median (IQR) | 1.12 (0.11) | 1.13 (0.11) |
Baseline Aβ positive (> 1.20), No, (%) | 43 (22) | 13 (28.9) |
Global Tau deposition, SUVR | ||
Baseline Tau retention, median (IQR) | 1.02 (0.14) | 1.00 (0.16) |