Table 1 Characteristics of the sample
CN Aβ − (n = 81) | CN Aβ + (n = 36) | MCI Aβ + (n = 31) | AD Aβ + (n = 18) | p-values | |
|---|---|---|---|---|---|
Age | 75.5 (32.5) | 78.0 (27.8) | 79.5 (30.1) | 84.5 (29.3) | < 0.001 |
Sex (M/F) | 34/47 | 19/17 | 16/15 | 9/9 | 0.654 |
Education | 18.0 (10.0) | 16.0 (8.0) | 16.0 (12.0) | 15.0 (7.0) | 0.017 |
APOE ε4 | 63/17/1 | 19/16/1 | 14/10/7 | 11/6/1 | < 0.001 |
Global Aβ SUVR | 1.0 (0.2) | 1.3 (0.6) | 1.4 (1.2) | 1.4 (0.8) | < 0.001 |
Braak I–II SUVR | 1.1 (0.5) | 1.1 (0.6) | 1.3 (1.0) | 1.5 (1.9) | < 0.001 |
Braak III–IV SUVR | 1.1 (0.5) | 1.2 (0.4) | 1.2 (0.9) | 1.4 (2.0) | < 0.001 |
Braak V–VI SUVR | 1.0 (0.4) | 1.0 (0.4) | 1.1 (0.9) | 1.1 (1.2) | < 0.001 |
ADAS 13 | 12.0 (21.7) | 13.3 (27.3) | 19.3 (27.0) | 32.3 (26.7) | < 0.001 |
ADAS Q4 | 2.0 (6.0) | 3.0 (7.0) | 5.0 (7.0) | 8.0 (5.0) | < 0.001 |
mPACC | 1.5 (15.5) | − 0.4 (19.0) | − 3.9 (16. 9) | − 14.9 (26.4) | < 0.001 |
CF | 22 (28) | 22 (22) | 16 (20) | 13.5 (14) | < 0.001 |
Trail A | 30 (48) | 32 (37) | 39 (50) | 51.5 (129) | < 0.001 |
Trail B | 2 (6) | 3 (7) | 5 (7) | 8 (5) | < 0.001 |