Table 1 Participant demographics
|  | Cognitively unimpaired (n = 259) | Early-stage dementia (n = 192) | P-value |
|---|---|---|---|
Age, years, mean (SD) | 61.83 (8.2) | 65.16 (9.28) |  < 0.001 |
Female, n (%) | 140/259 (54.1%) | 102/192 (53.1%) | 0.845 |
Education, years, mean (SD) | 13.05 (3.73) | 10.29 (3.73) |  < 0.001 |
APOE4 carrier, n (%) | 33/259 (12.7%) | 61/192 (31.8%) |  < 0.001 |
Total GMV, mean (SD) | 579.15 (54.3) | 555.59 (58.9) |  < 0.001 |
Total ICV, mean (SD) | 1356.23 (146.5) | 1357.83 (143.1) | 0.908 |
WMH Volume, mean (SD) | 6.87 (9.60) | 9.46 (12.81) | 0.015 |
MMSE, mean (SD) | 28.56 (1.28) | 25.14 (3.18) |  < 0.001 |
MoCA, mean (SD) | 27.80 (1.23) | 21.57 (2.85) |  < 0.001 |