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Fig. 7 | Alzheimer's Research & Therapy

Fig. 7

From: Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer’s disease in APP/PS1 mouse

Fig. 7

Neuronal loss in mouse brains. A Representative immunofluorescence images of neuron staining in CTX, CA1, and CA3. B–D Neurons in the CTX region were significantly reduced in AD + Saline (P < 0.05) and AD + Poly(I:C) mice (P < 0.05), and those in the CA1 and CA3 regions significantly decreased in AD + Saline mice (P < 0.05) but not in AD + Poly(I:C) mice compared with WT + Saline mice (#: WT + Saline vs. AD + Saline, P < 0.05; &: WT + Saline vs. AD + Poly(I:C), P < 0.05; *: AD + Saline vs. AD + Poly(I:C), P < 0.05; n = 4–6/group)

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Alzheimer's Research & Therapy

ISSN: 1758-9193