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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer’s disease in APP/PS1 mouse

Fig. 4

Aβ deposition in mouse brains. A Representative immunofluorescence images of Aβ deposition in mouse brains. B, C Representative Western blot images of Aβ deposition in the hippocampus and cortex. D, E Results from the quantitative analyses of Western blots showed that the Aβ levels were significantly higher in the AD + Saline mice and AD + Poly(I:C) mice than in the WT + Saline mice. However, compared with the AD + Saline mice, the Aβ levels were significantly lower in the AD + Poly(I:C) mice in the hippocampus but not in the cortex (#: WT + Saline vs. AD + Saline, P < 0.05; &: WT + Saline vs. AD + Poly(I:C), P < 0.05; *: AD + Saline vs. AD + Poly(I:C), P < 0.05; n = 4/group)

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