Fig. 1

Experimental design and survival rates of the mice in each group. A Experimental design: gene identification was performed on the mice. From 4 to 9 months of age, the mice in the treatment groups were administrated with Poly(I:C) through intraperitoneal injection at 5 mg/kg/4 days for 4 months. A battery of behavioral tests was performed, starting at 14 months old. The mice were killed by decapitation under deep anesthesia, and brain tissues were harvested for subsequent experiments at 14.5 months of age. B Survival rates of the mice in four groups’ post-treatment period were calculated. No statistical significance was found (P > 0.05)