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Table 1 Cognitive assessments in ROS/MAP/MARS and NACC used in the different composite scores

From: Rationale for the selection of dual primary endpoints in prevention studies of cognitively unimpaired individuals at genetic risk for developing symptoms of Alzheimer’s disease

Scale

ROS/MAP/MARS

NACC

Available

APCC

PACC proxy

RBANS proxy

Available

APCC proxy

PACC proxy

RBANS proxy

Boston Naming Test

X (15 items)

  

X

X (30 items)

X

 

X

Category fluency – Animals

X

  

X

X

X

 

X

Category fluency – Fruits/Vegetables

X

  

X

X

X

 

X

CERAD Word List Recall (immediate)

X

  

X

    

CERAD Word List Memory (delayed recall)

X

X

X

X

    

CERAD Word List Recognition

X

  

X

    

East Boston Naming Test, Immediate Recall (memory I)

X

       

East Boston Naming Test, Delayed Recall (memory II)

X

       

Logical Memory Ia (immediate)

X

  

X

X

  

X

Logical Memory IIa (delayed)

X

X

X

X

X

X

X

X

Digit Span – Forward

X

  

X

X

  

X

MMSE – Total

X

 

X

 

X

 

X

 

MMSE – Orientation to time

X

X

  

X

X

 

X

MMSE – Orientation to place

X

X

  

X

X

 

X

Ravens Progressive Matrices Subset (9 items)

X

X

 

X

    

Judgment of Line Orientation

X

X

 

X

    

Symbol Digit Modalities Test

X

X

X

X

    

WAIS Digit Symbol Substitution

    

X

X

X

X

  1. APCC Alzheimer’s Prevention Initiative Preclinical Composite Cognitive, CERAD Consortium to Establish a Registry for Alzheimer’s Disease, MMSE Mini-Mental State Examination, NACC National Alzheimer’s Coordinating Center, PACC Preclinical Alzheimer’s Cognitive Composite, RBANS Repeatable Battery for the Assessment of Neuropsychological Status, ROS/MAP/MARS Religious Orders Study/Memory and Aging Project/Minority Aging Research Study, WAIS Wechsler Adult Intelligence Scale