Table 1 Demographic and clinical characteristics of six groups of individuals
MCI (n=189) | AD (n=330) | VCI (n=57) | FTD (n=47) | DLB (n=21) | HC (n=246) | |
|---|---|---|---|---|---|---|
Age (years) | 64.77 ± 9.30 | 64.60 ± 9.75 | 67.18 ± 9.80 | 61.36 ± 8.69 | 72.01 ± 9.07 | 63.85 ± 8.20 |
Sex (male, %) | 68, 35.98 | 121, 36.67 | 31, 54.39 | 23, 48.94 | 13, 61.90 | 104, 42.28 |
ADO | 62.78 ± 9.42 | 61.80 ± 9.91 | 61.47 ± 11.06 | 61.74 ± 10.42 | 62.67 ± 10.49 | - |
COD | 1.98 ± 1.91 | 2.90 ± 2.49 | 1.75 ± 1.97 | 2.79 ± 1.65 | 2.00 ± 2.31 | - |
MMSE | 22.70 ± 4.48 | 11.63 ± 6.28 | 13.51 ± 6.98 | 12.20 ± 7.41 | 12.76 ± 6.44 | 28.62 ± 1.09 |
MoCA | 16.22 ± 5.01 | 7.02 ± 4.87 | 7.74 ± 4.86 | 7.68 ± 6.74 | 5.94 ± 5.65 | - |
Aβ42 (pg/ml) | 587.46 ± 439.59 | 408.29 ± 217.28 | - | - | - | - |
Aβ40 (pg/ml) | 8572.50 ± 6108.20 | 8286.91 ± 6000.22 | - | - | - | - |
Aβ42/40 | 0.09 ± 0.07 | 0.06 ± 0.04 | - | - | - | - |
t-tau (pg/ml) | 316.58 ± 289.84 | 506.21 ± 316.95 | - | - | - | - |
p-tau (pg/ml) | 76.79 ± 51.92 | 104.39 ± 51.94 | - | - | - | - |
APOE ε4 (%) | 43.86 (25/57) | 52.00 (78/150) |