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Table 8 Results of the mixed models analyses investigating the effect of a >= 35% increase in physical activity on serum concentrations 6 months after the start of the intervention (T1)

From: The effects of a moderate physical activity intervention on physical fitness and cognition in healthy elderly with low levels of physical activity: a randomized controlled trial

Outcome

 >  = 35% increase PA T2

N = 35

 < 35% increase PA T2

N = 38

Model A

N = 71

  

Model B

N = 71

  

Serum concentrations

Mean (sd)

Mean (sd)

B (95% CI)

P value

d

B (95% CI)

P value

d

IGF-I

 Baseline

14.55 (3.79)

13.87 (4.43)

      

 6 months

15.27 (3.80)

14.55 (3.79)

 − 0.25 (− 0.85 to 0.35)

.41a

.06

 − 0.31 (− 0.98 to 0.34)

.35a

.07

Insulin

 Baseline

53.84 (39.21)

51.93 (36.92)

      

 6 months

46.36 (46.01)

44.89 (22.09)

1.66 (− 3.74 to 7.05)

.55

.04

1.57 (− 4.33 to 7.48)

.60

.04

Total cholesterol

 Baseline

5.47 (1.25)

5.19 (1.15)

      

 6 months

5.58 (1.12)

5.18 (1.08)

0.02 (− 0.10 to 0.14)

.72

.02

0.03 (− 0.10 to 0.16)

.65

.03

HDL-cholesterol

 Baseline

1.41 (0.44)

1.45 (0.39)

      

 6 months

1.50 (0.44)

1.45 (0.39)

0.02 (− 0.02 to 0.06)

.38

.05

0.02 (− 0.02 to 0.07)

.34

.05

Triglycerides

 Baseline

1.43 (0.66)

1.62 (1.25)

      

 6 months

1.40 (0.74)

1.63 (0.96)

0.001 (− 0.13 to 0.13)

.99

0

 − 0.02 (− 0.16 to 0.12)

.76

.02

  1. aEffect moderation by sex observed. Model A: adjusted for y at baseline, age, and sex. Model B: adjusted for y at baseline, age, sex, education, and ApoE-ε4 carrier status
  2. PA Physical activity as measured in daily number of steps taken, ADL Activities of daily living, IGF-I Insulin-like growth factor 1, HDL High-density lipoprotein, d Cohen’s d