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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Krüppel-like factor 5 accelerates the pathogenesis of Alzheimer’s disease via BACE1-mediated APP processing

Fig. 1

KLF5 levels increase in Alzheimer’s disease (AD) and are associated with cognitive function. A KLF5 levels in the CSF of patients with different stages of AD and the normal cognition group (n = 30, respectively). B Relationship between the KLF concentration in the CSF (X-axis) and MMSE scores (Y-axis) of patients with AD (n = 60). C Relationship between the KLF concentration in the CSF (X-axis) and MoCA score (Y-axis) of patients with AD (n = 60). D Serum KLF5 levels of patients with different stages of AD (MCI, n = 30; DAT, n = 30) and the healthy control group (n = 40). E Relationship of the serum KLF concentration (X-axis) and MMSE score (Y-axis) of patients with AD (n = 60). F Relationship between the serum KLF concentration (X-axis) and MoCA score (Y-axis) of patients with AD (n = 60). G Serum KLF5 levels of APP/PS1 mice in different months (n = 3, respectively). ELISA data in A, D, and G are mean ± s.e.m (*P < 0.05, **P < 0.01, and ****P < 0.0001; one-way ANOVA). Data in B, C, E, and F are examined through linear regression analysis

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