Table 3 Influence of regional amyloid deposition on conversion to dementia
|  | Cutoff SUVR | AUC | Sensitivity (%) | Specificity (%) | P value | DeLong’s test P value |
|---|---|---|---|---|---|---|
L) Temporal cortex | 0.94203 | 0.678 (0.571–0.786) | 82.1 | 50.0 | < 0.001 |  |
R) Temporal cortex | 0.94333 | 0.624 (0.51–0.737) | 74.4 | 53.1 | < 0.001 |  |
L) Parietal cortex | 1.00438 | 0.762 (0.665–0.859) | 84.6 | 68.8 | < 0.001 |  |
R) Parietal cortex | 1.00589 | 0.724 (0.623–0.825) | 79.5 | 67.2 | < 0.001 |  |
L) Precuneus | 1.02879 | 0.721 (0.617–0.824) | 79.5 | 60.9 | < 0.001 |  |
L) Occipital cortex | 1.07716 | 0.703 (0.596–0.809) | 64.1 | 73.4 | < 0.001 |  |
FBB composite | 1.03224 | 0.708 (0.601–0.814) | 82.1 | 64.1 | < 0.001 |  |
DeLong’s test for the two correlated ROC curves | ||||||
 Model 1 | ||||||
  Left parietal SUVR + left precuneus SUVR + FBB composite |  | 0.763 (0.67–0.856) | 79.5 | 67.2 | 0.002 | 0.862 |
 Model 2 | ||||||
  Whole VOIs (bilateral temporal, bilateral parietal, left precuneus, left occipital, FBB composite) |  | 0.765 (0.673–0.857) | 76.9 | 68.8 | 0.002 |  |