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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Effect of the ABCA1 agonist CS-6253 on amyloid-β and lipoprotein metabolism in cynomolgus monkeys

Fig. 5

Analysis of pre-β HDL and s-, m-, and l-HDL particles in plasma. A Plasma pre-β HDL levels in the PK study were measured by ELISA assay (n = 2). B Plasma pre-β1 HDL levels were determined using ion-mobility analysis and Voigt probability distribution (see also Fig S7) for one monkey in the PK study. C For the same monkey, plasma s-, m-, and l-HDL particle concentrations were calculated using ion-mobility analysis and Voigt probability distribution. D For one monkey in the DRF study, plasma pre-β HDL levels were determined using ion-mobility analysis and Voigt probability distribution. E For the same monkey, plasma s-, m-, and l-HDL particle concentrations were calculated using ion-mobility analysis and Voigt probability distribution

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