Fig. 8

Tracer uptake for 5xFAD mice, relative to the uptake obtained for age-matched WT animals, in the cortex (CTX) and hippocampus (HC) at different ages and using different tracers. The red line (right Y axis), corresponding to [¹⁸F]florbetaben, represents age-matched 5xFAD/WT ratios of SUVr to the cerebellum; the blue line (right Y axis), corresponding to [¹⁸F]DPA-714, represents age-matched 5xFAD/WT ratios of DVR; the green line (left Y axis), corresponding to [¹⁸F]FSPG, represents age-matched 5xFAD/WT ratios of SUV