From: Dynamic functional connectivity patterns associated with dementia risk
N = 127 | ||||
---|---|---|---|---|
Mean | sd | min | max | |
Demographic | ||||
Age (years) | 68.9 | 3.82 | 65.0 | 83.0 |
Sex (% of women) | 63.8 % | - | - | - |
Education (years) | 13.1 | 3.14 | 7.0 | 22.0 |
Clinical characteristics | ||||
Fasting blood sugar (g/L) | 1.0 | 0.2 | 0.7 | 2.1 |
Body mass index (kg/m2) | 26.1 | 4.3 | 18.1 | 44.2 |
Systolic blood pressure (mmHg) | 135 | 20.4 | 87.7 | 198 |
LDL cholesterol (g/L) | 1.6 | 0.4 | 0.7 | 2.8 |
Depressive symptoms (GDS) | 1.3 | 1.8 | 0 | 11 |
Lifestyle characteristics | ||||
Smoking (pack years) | 7.13 | 12.8 | 0 | 75.0 |
Alcohol consumption (unit per week) | 4.7 | 5.0 | 0 | 24.5 |
Engagement in stimulating activities | ||||
Early-life LEQ | 31.2 | 9.3 | 10.0 | 52.8 |
Mid-life LEQ | 38.3 | 8.5 | 19.8 | 65.7 |
Late-life LEQ | 28.1 | 4.55 | 17.4 | 38.4 |
Cognitive activity | ||||
Early-life CAQ | 17.4 | 3.2 | 8.0 | 27.0 |
Mid-life CAQ | 16.9 | 3.5 | 5.0 | 25.0 |
Late-life CAQ | 17.4 | 3.2 | 8.0 | 24.0 |
Physical activity (PASE) | 129.0 | 60.8 | 21.5 | 330.0 |
Cognition | ||||
PACC5 (z-score) | 0.004 | 0.65 | -1.86 | 1.76 |
Neuroimaging | ||||
Amyloid load (late florbetapir-PET amyloid SUVR) | 1.25 | 0.16 | 0.99 | 1.82 |
Brain perfusion (early florbetapir-PET SUVR) | 1.01 | 0.06 | 0.87 | 1.20 |
Hippocampal volume (mm3) | 2460 | 249 | 1740 | 3150 |
Genetics | ||||
APOE4 status (% ≥ 1 allele E4 ) | 26% | - | - | - |