Table 1 Baseline characteristics for study participants by clinical trial (n = 1495)
From: Subclinical carotid artery atherosclerosis and cognitive function in older adults
Variable | BVAIT (n = 504)a | WISH (n = 349)a | ELITE (n = 642)a | Combined |
|---|---|---|---|---|
Mean ± SD or number (%) | ||||
Age (years) | 61.5 ± 9.9 | 61.4 ± 7.1 | 60.6 ± 6.9 | 61.1 ± 8.1 |
Sex | ||||
 Male | 308 (61.1%) | 0 (0%) | 0 (0%) | 308 (20.6%) |
 Female | 196 (38.9%) | 349 (100%) | 642 (100%) | 1187 (79.4%) |
Race | ||||
 Non-Hispanic White | 326 (64.7%) | 222 (63.6%) | 439 (68.4%) | 987 (66.0%) |
 Non-Hispanic Black | 75 (14.9%) | 21 (6.0%) | 60 (9.3%) | 156 (10.4%) |
 Hispanic | 55 (10.9%) | 55 (15.8%) | 90 (14.0%) | 200 (13.4%) |
 Asian or Pacific Islander | 45 (8.9%) | 38 (10.9%) | 53 (8.3%) | 136 (9.1%) |
 Others | 3 (0.6%) | 13 (3.7%) | 0 (0%) | 16 (1.1%) |
Education (# of years) | 15.7 ± 2.0b | 15.8 ± 2.0 | 16.0 ± 1.9 | 15.9 ± 2.0 |
Annual income | $64.6k ± $29.7kb | $65.3k ± $31.3kb | $69.0k ± $31.0kb | $66.7k ± $30.7k |
Marital status | ||||
 Single, never married | 45 (8.9%)b | 33 (9.5%) | 50 (7.8%) | 128 (8.6%) |
 Married | 323 (64.1%)b | 197 (56.4%) | 368 (57.3%) | 888 (59.4%) |
 Separated | 5 (1.0%)b | 7 (2.0%) | 12 (1.9%) | 24 (1.6%) |
 Divorced | 89 (17.7%)b | 80 (22.9%) | 171 (26.6%) | 340 (22.8%) |
 Widowed | 41 (8.1%)b | 32 (9.2%) | 41 (6.4%) | 114 (7.6%) |
Current smoker | 17 (3.4%)b | 8 (2.3%) | 22 (3.4%) | 47 (3.2%) |
Alcohol user | 221 (43.8%) | 152 (43.6%) | 313 (48.8%) | 686 (45.9%) |
Use of anti-hypertensives at baseline | 190 (37.7%) | 117 (33.5%) | 220 (34.3%) | 527 (35.3%) |
Use of cholesterol lowering medication at baseline | 81 (16.1%) | 72 (20.6%) | 126 (19.6%) | 279 (18.7%) |
BMI (kg/m2) | 28.1 ± 4.9 | 26.6 ± 5.2 | 27.2 ± 5.4b | 27.4 ± 5.2 |
Blood pressure (mmHg) | ||||
 Systolic | 127.0 ±15.6 | 117.9 ± 13.9 | 116.5 ± 13.7b | 120.4 ± 15.2 |
 Diastolic | 78.7 ± 8.9 | 75.0 ± 8.6 | 74.5 ± 8.4b | 76.0 ± 8.8 |
ApoE4+ | 103 (22.2%)b | 86 (25.7%)b | 197 (30.9%)b | 386 (26.9%) |
CES-D scorec | 6.2 ± 6.6 | 7.3 ± 6.82 | 8.3 ± 8.6 | 7.4 ± 7.6 |
CES-D score ≥ 16d | 44 (8.7%) | 40 (11.5%) | 113 (17.6%) | 197 (13.2%) |
Average CIMT (mm, over 1 cm segment) | 0.75 ± 0.15 | 0.81 ± 0.10 | 0.77 ± 0.11 | 0.77 ± 0.12 |
Executive function composite score | − 0.012 ± 1.369 | − 0.005 ± 1.323 | − 0.002 ± 1.360 | − 0.006 ± 1.353 |
Verbal memory composite score | − 0.005 ± 1.317 | − 0.006 ± 1.357 | 0.001 ± 1.348 | − 0.003 ± 1.339 |
Visual memory composite score | 0.001 ± 1.108 | 0.001 ±1.107 | 0 ± 1.103 | 0.001 ± 1.105 |
Global cognition composite score | 0.014 ± 1.745 | 0.002 ± 1.715 | − 0.001 ± 1.827 | 0.005 ± 1.773 |