From: Validation of amyloid PET positivity thresholds in centiloids: a multisite PET study approach
[18F]florbetaben cohort | [18F]florbetapir cohort | ||||||
---|---|---|---|---|---|---|---|
[11C]PiB | [11C]PiB | ||||||
SUVR | CL | SUVR | CL | ||||
Elderly | Mean | 1.72 | 66.00 | Elderly | Mean | 1.62 | 57.26 |
SD | 0.57 | 52.91 | SD | 0.55 | 51.07 | ||
CV (%) | 33 | CV (%) | 34 | ||||
YC | Mean | 1.00 | −1.21 | YC | Mean | 1.00 | −1.11 |
SD | 0.04 | 3.57 | SD | 0.04 | 3.45 | ||
CV (%) | 4 | CV (%) | 4 | ||||
[18F]florbetaben | [18F]florbetapir | ||||||
SUVR | CL | SUVR | CL | ||||
Elderly | Mean | 1.38 | 65.40 | Elderly | Mean | 1.31 | 57.01 |
SD | 0.35 | 55.29 | SD | 0.29 | 55.00 | ||
CV (%) | 25 | CV (%) | 22 | ||||
YC | Mean | 0.97 | 0.25 | YC | Mean | 1.00 | −0.43 |
SD | 0.03 | 4.83 | SD | 0.05 | 9.99 | ||
CV (%) | 3 | CV (%) | 5 | ||||
FBB/PiB SD ratio 1.35 | FBP/PiB SD ratio 2.89 |