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Table 1 Characteristics of included patients

From: COVID-19 in adults with dementia: clinical features and risk factors of mortality—a clinical cohort study on 125 patients

 

Total (n = 125)

Survivors (n = 97)

Non-survivors (n = 28)

p

Age

86 (82–91)

87 (82–91)

86 (82–93)

0.815

Male sex

41.6% (52)

36.1% (35)

60.7% (17)

0.029

Admission from:

   

0.663

 Home

59.2% (74)

57.7% (56)

64.3% (18)

 

 Long-term care facility

40.8% (51)

42.3% (41)

35.7% (10)

 

Medical history

 Comorbidities

91.2% (114)

91.8% (89)

89.3% (25)

0.709

 > 2 Comorbidities

67.2% (84)

67.0% (65)

67.9% (19)

0.822

 Charlson Comorbidity Index

6 (5–7)

6 (5–7)

6 (5–7)

0.292

Neurological status

Etiologies of dementia

  Unspecified cognitive impairment

60.0% (75)

59.8% (58)

60.7% (17)

1.000

  Diagnosed dementia

40.0% (50)

40.2% (39)

39.3% (11)

1.000

  Alzheimer’s disease

10.4% (13)

11.3% (11)

7.1% (2)

0.731

  Vascular dementia

7.2% (9)

6.2% (6)

10.7% (3)

0.418

  Other causes of dementia

7.2% (9)

5.2% (5)

14.3% (4)

0.113

  Parkinson disease, parkinsonian syndromes

9.6% (12)

10.3% (10)

7.1% (2)

1.000

  Psychosis

3.2% (4)

4.1% (4)

0.0% (0)

1.000

  Alcohol-related dementia

2.4% (3)

3.1% (3)

0.0% (0)

1.000

Neurological symptoms and history

  Mood disorder

31.2% (39)

33.0% (32)

25.0% (7)

0.640

  Psychotic symptoms

12.0% (15)

12.4% (12)

10.7% (3)

1.000

  History of stroke

32.0% (40)

32.0% (31)

32.1% (9)

1.000

  History of fall

38.4% (48)

36.1% (35)

46.4% (13)

0.373

  Walking before admission

70.4% (88)

70.1% (68)

71.4% (20)

1.00

  Psychotropic treatment

60.0% (75)

60.8% (59)

57.1% (16)

0.826

  Anxiolytic

30.4% (38)

32.0% (31)

25.0% (7)

0.642

  Antidepressant, mood regulator

35.2% (44)

35.1% (34)

35.7% (10)

1.000

  Neuroleptics

12.0% (15)

11.3% (11)

14.3% (4)

0.742

Non-neurological comorbidities

 Cardiovascular disease

40.8% (51)

38.1% (37)

50.0% (14)

0.383

 Arterial hypertension

80.0% (100)

79.4% (77)

82.1% (23)

1.00

 Hypercholesterolaemia

48.8% (61)

46.4% (45)

57.1% (16)

0.392

 Atrial fibrillation

24.8% (31)

24.7% (24)

25.0% (7)

1.00

 Coronaropathy

16.0% (20)

14.4% (14)

21.4% (6)

0.388

 Cardiac insufficiency

24.0% (30)

25.8% (25)

17.9% (5)

0.460

 Thrombosis

9.6% (12)

11.3% (11)

3.6% (1)

0.296

 COPD

8.8% (11)

6.2% (6)

17.9% (5)

0.068

 Respiratory insufficiency

3.2% (4)

3.1% (3)

3.6% (1)

1.000

 Diabetes

16.8% (21)

15.5% (15)

21.4% (6)

0.566

 Malnutrition

33.6% (42)

37.1% (36)

21.4% (6)

0.172

 Malignancy

9.6% (12)

11.3% (11)

3.6% (1)

0.296

 Chronic liver disease

1.6% (2)

2.1% (2)

0.0% (0)

1.000

 Chronic renal disease

16.0% (20)

11.3% (11)

32.1% (9)

0.017

  1. Data are median (IQI), % (n). P values > 0.05 (bold) indicates significant differences between survivors and non-survivors
  2. *Other causes of dementia: included mixed dementia (AD and vascular dementia, n = 7), fronto-temporal dementia (n = 1) and vascular dementia and alcohol-related dementia (respectively, n = 1)
  3. COPD chronic obstructive pulmonary disease