From: Quality of opioid prescribing in older adults with or without Alzheimer disease and related dementia
Medication | Community | Nursing home | ||||||
---|---|---|---|---|---|---|---|---|
Weighted proportion among patients with ADRD, % | Weighted proportion among patients without ADRD, % | Proportion difference (95% CI)a | P-value | Weighted proportion among patients with ADRD, % | Weighted proportion among patients without ADRD, % | Proportion difference (95% CI)a | P-value | |
Any use of prescription pain medicationb,c | 66.6 | 67.6 | − 1.0 (− 1.4 to − 0.7) | < .001 | 64.5 | 74.9 | − 10.4 (− 11.7 to − 9.1) | < .001 |
Opioid | ||||||||
Any use | 45.1 | 48.1 | − 3.0 (− 3.4 to − 2.6) | < .001 | 47.9 | 60.7 | − 12.8 (− 14.2 to − 11.3) | < .001 |
Long-term use of opioidd | 41.2 | 35.7 | 5.4 (4.9 to 6.0) | < .001 | 52.5 | 58.2 | − 5.7 (−7.6 to − 3.8) | < .001 |
Non-opioid | ||||||||
Any use | 30.3 | 32.7 | − 2.4 (− 2.8 to − 2.1) | < .001 | 18.0 | 21.9 | − 3.9 (− 5.1 to − 2.7) | < .001 |
Adjuvant analgesic | ||||||||
Any use | 35.9 | 32.7 | 3.1 (2.8 to 3.5) | < .001 | 33.2 | 40.9 | − 7.6 (− 9.1 to − 6.2) | < .001 |
SNRI or tricyclic antidepressant | 40.0 | 26.8 | 13.1 (12.7 to 13.5) | < .001 | 59.4 | 53.3 | 6.1 (4.6 to 7.6) | < .001 |
Anticonvulsant | 21.1 | 17.7 | 3.4 (3.1 to 3.7) | < .001 | 21.9 | 27.2 | − 5.3 (− 6.7 to − 4.0) | < .001 |
Skeletal muscle relaxant | 14.2 | 15.6 | − 1.4 (− 1.7 to − 1.2) | < .001 | 8.2 | 14.8 | − 6.7 (− 7.7 to − 5.6) | < .001 |
Topical analgesice | 8.1 | 6.6 | 1.5 (1.3 to 1.7) | < .001 | 8.8 | 11.9 | − 3.0 (− 4.0 to − 2.1) | < .001 |