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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Comorbidity between Alzheimer’s disease and major depression: a behavioural and transcriptomic characterization study in mice

Fig. 5

Distribution pattern of differentially expressed genes from the APP/PSEN1-Tg mouse model. Total number of up- (red bars) and downregulated (blue bars) genes within the amygdala, hippocampus, striatum and PFC at a 3 months and b 6 months. Venn diagrams show the number of differentially expressed genes among areas, in an upregulated (c, d) and downregulated (f, g) way. Venn diagrams show the number of upregulated (e) and downregulated (h) shared genes between 3 and 6 months old of age APP/PSEN1-Tg (n = 6 per group) vs non-transgenic mice (n = 6 per group)

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Alzheimer's Research & Therapy

ISSN: 1758-9193