Control, β (p) | Intervention, β (p) | Interaction, p | |
---|---|---|---|
Change in cognition | |||
NTB total composite | 0.11 (0.62) | − 0.46 (0.04) | 0.07 |
NTB memory | 0.12 (0.58) | − 0.54 (0.01) | 0.02 |
NTB processing speed | −0.04 (0.85) | 0.24 (0.31) | 0.41 |
NTB executive function | 0.12 (0.59) | −0.31 (0.17) | 0.18 |
Change in MRI | |||
Total gray matter volume | 0.18 (0.45) | −0.39 (0.10) | 0.08 |
Hippocampal volume | 0.06 (0.79) | −0.28 (0.25) | 0.30 |
AD signature cortical thickness | 0.05 (0.84) | −0.20 (0.42) | 0.50 |
White matter lesion volume | −0.05 (0.82) | −0.05 (0.85) | 0.97 |
Change in FDG-PET | |||
Cortical composite | 0.24 (0.32) | 0.01 (0.97) | 0.42 |
Prefrontal cortex | 0.08 (0.74) | 0.04 (0.89) | 0.85 |
Parietal cortex | 0.21 (0.36) | 0.11 (0.70) | 0.68 |
Lateral temporal cortex | 0.20 (0.40) | −0.03 (0.91) | 0.46 |
Precuneus | 0.23 (0.33) | −0.04 (0.89) | 0.41 |
Anterior cingulate gyrus | 0.25 (0.29) | −0.05 (0.85) | 0.34 |
Posterior cingulate gyrus | 0.26 (0.27) | 0.00 (0.99) | 0.34 |
Medial temporal cortex | 0.25 (0.30) | 0.13 (0.64) | 0.59 |
Lateral occipital cortex | 0.23 (0.32) | −0.28 (0.29) | 0.18 |
Striatum | 0.38 (0.10) | −0.08 (0.77) | 0.15 |
Cerebellum | −0.01 (0.97) | 0.22 (0.41) | 0.50 |
Change in PIB-PET | |||
Cortical composite | −0.04 (0.87) | −0.10 (0.69) | 0.81 |