Table 1 Sample demographics

n

307

56

251

57

250

Sex (F/M)

149/158

25/31

124/127

23/34

126/124

Aβ42 (pg/ml)^a

753 [145–1200]

396 [145–628]

792 [304–1200]

735 [195–1180]

761 [145–1200]

Total tau (pg/ml)^a

299 [115–963]

412 [225–963]

287 [115–800]

303 [144–634]

298 [115–963]

Phospho-tau (pg/ml)^a

48 [18–128]

59 [35–128]

45 [18–113]

49 [23–84]

47 [18–128]

Aβ40 (pg/ml)^a

6262 [2752–9968]

6618 [3661–9760]

6121 [2752–9968]

6042 [3175–8268]

6271 [2752–9968]

Aβ42/Aβ40 ratio

0.123 [0.022–0.210]

0.061 [0.022–0.081]

0.129 [0.083–0.210]

0.122 [0.034–0.199]

0.123 [0.022–0.210]

NfL (pg/ml)^a

732 [255–12,312]

783 [302–3124]

711 [255–12,312]

720 [255–6233]

724 [276–12,312]

Neurogranin (pg/ml)^a

197 [54–513]

224 [120–410]

188 [54–513]

199 [54–374]

196 [72–513]

APOE ε4 carrier (Y/N/NA)

108/196/3

38/17/1

70/179/2

27/30/0

81/166/3

APOE genotype (22/32/33/42/43/44/NA)

1/37/158/4/95/9/3

0/2/15/2/29/7/1

1/35/143/2/66/2/2

0/6/24/1/23/3/0

1/31/134/3/74/6/3

CDR score (0/0.5/1)

250/56/1

45/11/0

205/45/1

0/56/1

250/0/0