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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer’s disease progression based on the “brain-gut” axis through multiple integrated omics

Fig. 5

Schematic diagram of gut-brain axis in AD progression and the intervention strategy. During AD progression, peripheral inflammation was highly correlated with neuroinflammation suggests that altered systemic inflammatory markers reflect neurodegenerative disease. HLJDD attenuated brain damage and memory deficits in Tg-APP/PS1 mice by coordinating CNS inflammation and peripheral inflammation. Red arrow: represent a major change in Tg mice. Green arrow: represent a major change that occurs after the HLJDD group

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Alzheimer's Research & Therapy

ISSN: 1758-9193