Overall | APOE ε4 non-carriers | APOE ε4 carriers | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
β [95% CI] | t | df | p value | β [95% CI] | t | df | p value | β [95% CI] | t | df | p value | |
ARBs vs. ACE-Is | 0.050[0.001, 0.099] | 1.98 | 533.5 | 0.0483 | 0.085[0.012, 0.158] | 2.28 | 533.9 | 0.0230 | 0.0471[− 0.012, 0.106] | 1.56 | 558.9 | 0.1186 |
C-ARBs vs. NC-ACE-Is | 0.044[− 0.012, 0.101] | 1.54 | 586.1 | 0.1252 | 0.106[0.026, 0.185] | 2.60 | 647.9 | 0.0095 | 0.020 [− 0.051, 0.091] | 0.55 | 574.0 | 0.5852 |
C-ACE-Is vs. NC-ACE-Is | 0.012[− 0.061, 0.086] | 0.33 | 562.0 | 0.7388 | 0.055[− 0.050, 0.161] | 1.03 | 708.9 | 0.3035 | − 0.023[− 0.115, 0.069] | − 0.49 | 487.1 | 0.6224 |
NC-ARBs vs. NC-ACE-Is | 0.043[− 0.016, 0.102] | 1.42 | 600.3 | 0.1560 | 0.074[− 0.009, 0.158] | 1.74 | 694.8 | 0.0816 | 0.024[− 0.049, 0.098] | 0.65 | 523.3 | 0.5177 |
C-ARBs vs. NC-ARBs | 0.005[− 0.046, 0.055] | 0.18 | 609.9 | 0.8567 | 0.037[− 0.030, 0.104] | 1.08 | 994.6 | 0.2822 | − 0.003[− 0.062, 0.056] | − 0.09 | 851.0 | 0.9292 |
C-ARBs vs. C-ACE-Is | 0.036[− 0.010, 0.082] | 1.53 | 853.1 | 0.1250 | 0.070[0.003, 0.136] | 2.06 | 606.4 | 0.0400 | 0.035[− 0.020, 0.090] | 1.24 | 678.5 | 0.2147 |