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Table 3 Approximate conditional analysis on tissue-specific allelic series in ACE eQTLs

From: Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traits

Tissue of ACE eQTL

P value of rs4308 conditioned on rs4324

Effect of rs4308 on the ACE eQTL conditioned on rs4324

P value of rs4324 conditioned on rs4308

Effect of rs4324 on the ACE eQTL conditioned on rs4308

Lung

0.15

0.048

2.57e−08

0.18

Cerebellum

5.34e−04

− 0.25

0.66

− 0.034

Kidney cortex

4.41e−08

0.49

0.21

− 0.14

  1. Approximate conditional analyses performed on the leading single-tissue eQTLs at the ACE locus
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Alzheimer's Research & Therapy

ISSN: 1758-9193