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Table 3 Adjusted odds ratio and 95% confidence intervals for model 1 (ADP versus LRP) and model 2(ADP versus ADP-LRP). Logistic regression model with APOE e4 is the exposure, initial cognitive as outcomes, and pathology as subgroups and age, sex, and education as covariates. Significant results (p < 0.05) are in bold. Model 1: ADP versus LRP

From: Impact of APOE ε4 genotype on initial cognitive symptoms differs for Alzheimer’s and Lewy body neuropathology

 

Amnestic

Executive/attention concentration

Language

Visualspatial

APOEε4 odds in ADP

1.58 (1.17–2.14)

0.99 (0.61–1.60)

0.67 (0.47–0.96)

0.46 (0.20–0.99)

Age at visit

1.1 (1.08–1.1)

0.93 (0.92–0.96)

0.93 (0.92–0.95)

0.92 (0.89–0.95)

Sex, female

0.75 (0.56–1.01)

0.73 (0.45–1.17)

1.71 (1.2–2.4)

0.99 (0.47–2.03)

Education, years

0.96 (0.91–1.01)

1.0 (0.92–1.08)

1.07 (1.01–1.14)

1.0 (0.89–1.13)

  1. Adjusted odds ratio for LRP as a reference not presented due to smaller cell counts