RETRACTED ARTICLE: Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis

Table 4 Percentage pyknotic cells in treated and untreated 5xFAD and age-matched WT mice. *p < 0.05; **p < 0.01 compared to WT + vehicle and WT + SLCP. ↓ decrease, m month

Groups	Pyknotic cells
	PFC		CA1		CA3		EC
	6 m	12 m	6 m	12 m	6 m	12 m	6 m	12 m
5xFAD + vehicle	22.98**	31.91**	22.14**	36.12**	29.16**	44.89**	20.73	29.79
5xFAD + SLCP	14.15*	18.41*	9.86**	18.27**	22.38**	24.34**	13.17*	15.13*
% ↓ pyknotic cells by SLCP treatment	38.45	42.29	55.45	49.40	23.25	45.76	36.48	49.19
5xFAD + vehicle	36.27	45.89	19.09	20.14	20.88	54.37	Degenerated neurons (fluoro-jade C staining)
5xFAD + SLCP	24.03*	24.00**	7.00*	7.22*	16.50	39.37**
% ↓ FJC + neurons by SLCP treatment	33.73	47.70	63.33	64.11	21.01	26.55

ISSN: 1758-9193