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Table 1 Sample description reported for all randomized participants with a reported study partner type. Quantitative variables are summarized as mean (standard deviation) and categorical variables as N (%)

From: Recruitment and retention of participant and study partner dyads in two multinational Alzheimer’s disease registration trials

 

Study partner type

Totald (N = 2635)

Spouse (N = 1729)

Adult child (N = 662)

Other (N = 244)

Participant age

71.81 (7.9)

75.77 (7.8)

74.87 (8.4)

73.09 (8.1)

Education (years)

13.07 (3.9)

10.61 (4.1)

11.13 (4.1)

12.27 (4.1)

Sex: female

750 (43%)

519 (78%)

189 (77%)

1458 (55%)

Regiona

 North America

722 (42%, 73%)

172 (26%, 17%)

89 (36%, 9%)

983 (37%)

 South America/Mexico

87 (5%, 43%)

77 (12%, 38%)

39 (16%, 19%)

203 (8%)

 Eastern Europe/Russia

111 (6%, 38%)

153 (23%, 53%)

25 (10%, 9%)

289 (11%)

 Western Europe/Israel

413 (24%, 75%)

100 (15%, 18%)

36 (15%, 7%)

549 (21%)

 Australia/South Africa

113 (7%, 74%)

22 (3%, 14%)

18 (7%, 12%)

153 (6%)

 Asia

112 (6%, 55%)

74 (11%, 36%)

18 (7%, 9%)

204 (8%)

 Japan

171 (10%, 67%)

64 (10%, 25%)

19 (8%, 7%)

254 (10%)

Race/ethnicity

 Caucasian

1364 (79%)

452 (68%)

174 (71%)

1990 (76%)

 Asian

292 (17%)

142 (21%)

40 (16%)

474 (18%)

 Hispanic

57 (3%)

59 (9%)

24 (10%)

140 (5%)

 African American/Black

16 (1%)

9 (1%)

6 (2%)

31 (1%)

Baseline assessments

 Mini-Mental State Exam

20.94 (3.2)

20.06 (3.0)

20.66 (3.0)

20.69 (3.1)

 ADAS-cog

23.06 (9.0)

24.7 (9.0)

23.16 (8.7)

23.48 (9.0)

 Activities of Daily Living

61.08 (12.2)

57.42 (14.5)

58.72 (14.6)

59.95 (13.1)

 Hachinski Scoreb

1 (0, 1)

1 (0, 1)

1 (0, 1)

1 (0, 1)

 Geriatric Depression Scaleb

2 (1, 3)

2 (1, 3)

2 (1, 3)

2 (1, 3)

Study partner

 Age

70.56 (8.7)

48.08 (9.0)

56.02 (14.5)

63.57 (13.7)

 Contribution levelb,c

5 (5, 5)

4 (3, 5)

4 (3, 5)

5 (4, 5)

 Sex: female

972 (56%)

457 (69%)

200 (82%)

1629 (62%)

 Paid job

385 (22%)

451 (68%)

119 (49%)

955 (36%)

  1. a(Column %, Row %) are reported for region
  2. bSummarized as median (25%, 75%)
  3. cContribution level among all caregivers is measured on a scale from 1 (1–20%) to 5 (81–100%)
  4. dTwo participants were excluded for having a race of 'other' and one was excluded for missing partner type