From: The insulin resistance by triglyceride glucose index and risk for dementia: population-based study
TyG index | Events (n) | Duration (person-years) | Incidence rate (per 1000 person-years) | Unadjusted | Model 1 | Model 2 |
---|---|---|---|---|---|---|
All-cause dementia | HR (95% CI) | HR (95% CI) | HR (95% CI) | |||
Q1 | 26,613 | 10,089,076.34 | 2.64 | 1 (ref.) | 1 (ref.) | 1 (ref.) |
Q2 | 32,819 | 10,074,648.59 | 3.26 | 1.23 (1.22, 1.26) | 1.03 (1.01, 1.04) | 1.04 (1.02, 1.05) |
Q3 | 38,606 | 10,066,646.27 | 3.84 | 1.45 (1.43, 1.48) | 1.05 (1.04, 1.07) | 1.07 (1.05, 1.09) |
Q4 | 44,676 | 10,041,387.42 | 4.45 | 1.69 (1.66, 1.71) | 1.11 (1.09, 1.13) | 1.14 (1.12, 1.16) |
p for trend | < 0.001 | < 0.001 | < 0.001 | |||
AD | ||||||
Q1 | 19,705 | 10,089,076.34 | 1.95 | 1 (ref.) | 1 (ref.) | 1 (ref.) |
Q2 | 24,354 | 10,074,648.59 | 2.42 | 1.24 (1.21, 1.26) | 1.02 (1.00, 1.03) | 1.03 (1.01, 1.05) |
Q3 | 28,661 | 10,066,646.27 | 2.85 | 1.46 (1.43, 1.48) | 1.03 (1.01, 1.05) | 1.05 (1.03, 1.07) |
Q4 | 33,298 | 10,041,387.42 | 3.32 | 1.70 (1.67, 1.73) | 1.07 (1.06, 1.09) | 1.12 (1.09, 1.14) |
p for trend | < 0.001 | < 0.001 | < 0.001 | |||
VD | ||||||
Q1 | 3341 | 10,089,076.34 | 0.33 | 1 (ref.) | 1 (ref.) | 1 (ref.) |
Q2 | 4110 | 10,074,648.59 | 0.41 | 1.23 (1.18, 1.29) | 1.08 (1.03, 1.13) | 1.05 (1.01, 1.10) |
Q3 | 4779 | 10,066,646.27 | 0.47 | 1.43 (1.37, 1.50) | 1.14 (1.09, 1.19) | 1.09 (1.05, 1.15) |
Q4 | 5570 | 10,041,387.42 | 0.55 | 1.68 (1.61, 1.75) | 1.25 (1.20, 1.31) | 1.18 (1.12, 1.23) |
p for trend | < 0.001 | < 0.001 | < 0.001 |