Table 3 Estimates of the fixed and random parts of the models with interaction of the baseline grouping with ADAM10, and random effect on the intercept, using MMSE score values on follow-up as the dependent variable

Fixed effects

Estimate

SE

p

Estimate

SE

p

Intercept

1.72

0.82

0.03

10.93

1.60

< 0.001

Age, years

–

–

–

− 0.11

0.01

< 0.001

Male sex

–

–

–

0.17

0.25

0.4

Altered MMSE: ADAM10 (ng/mL)

− 0.08

0.1

0.4

− 0.1

0.1

0.2

Normal MMSE: ADAM10 (ng/mL)

− 0.2

0.08

0.001

− 0.2

0.08

0.001

Baseline MMSE score

0.93

0.03

< 0.001

0.88

0.03

< 0.001

Random effects

Variance

Variance

Individuals (intercept)

0.0

0.0

Residuals

6.64

6.0

Bayesian information criterion