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Table 2 Estimates of the fixed and random parts of the models with random effect on the intercept, using MMSE score values on follow-up as the dependent variable

From: ADAM10 plasma levels predict worsening in cognition of older adults: a 3-year follow-up study

  Model 1 Model 2 Model 3
Fixed effects Estimate SE p Estimate SE p Estimate SE p
Intercept 24.09 0.38 < 0.001 37.73 2.33 < 0.001 10.19 1.73 < 0.001
Age, years − 0.20 0.03 < 0.001 − 0.11 0.01 < 0.001
Male sex 0.94 0.46 0.04 0.18 0.25 0.4
Baseline altered MMSE − 5.04 0.54 < 0.001 − 4.79 0.49 < 0.001 0.60 0.35 0.08
ADAM10, ng/mL − 0.2 0.1 0.03 − 0.2 0.1 0.02 − 0.2 0.07 0.003
Baseline MMSE score 0.90 0.03 < 0.001
Random effects Variance SD Variance SD Variance SD
Individuals (intercept) 9.38 3.06 7.21 2.69 0.0 0.0
Residuals 7.01 2.65 7.01 2.65 6.02 2.45
Bayesian information criterion 2175 2148 1871
  1. SE standard error, SD standard deviation, MMSE Mini-Mental State Examination
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