From: ADAM10 plasma levels predict worsening in cognition of older adults: a 3-year follow-up study
Model 1 | Model 2 | Model 3 | |||||||
---|---|---|---|---|---|---|---|---|---|
Fixed effects | Estimate | SE | p | Estimate | SE | p | Estimate | SE | p |
Intercept | 24.09 | 0.38 | < 0.001 | 37.73 | 2.33 | < 0.001 | 10.19 | 1.73 | < 0.001 |
Age, years | – | – | – | − 0.20 | 0.03 | < 0.001 | − 0.11 | 0.01 | < 0.001 |
Male sex | – | – | – | 0.94 | 0.46 | 0.04 | 0.18 | 0.25 | 0.4 |
Baseline altered MMSE | − 5.04 | 0.54 | < 0.001 | − 4.79 | 0.49 | < 0.001 | 0.60 | 0.35 | 0.08 |
ADAM10, ng/mL | − 0.2 | 0.1 | 0.03 | − 0.2 | 0.1 | 0.02 | − 0.2 | 0.07 | 0.003 |
Baseline MMSE score | – | – | – | – | – | – | 0.90 | 0.03 | < 0.001 |
Random effects | Variance | SD | Variance | SD | Variance | SD | |||
Individuals (intercept) | 9.38 | 3.06 | 7.21 | 2.69 | 0.0 | 0.0 | |||
Residuals | 7.01 | 2.65 | 7.01 | 2.65 | 6.02 | 2.45 | |||
Bayesian information criterion | 2175 | 2148 | 1871 |