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Table 3 Correlation between cerebrospinal fluid FL-Ng, CT-Ng, SNAP-25, synaptotagmin, 215–223, and synaptotagmin, 238–245 levels for the clinical studya

From: Full-length and C-terminal neurogranin in Alzheimer’s disease cerebrospinal fluid analyzed by novel ultrasensitive immunoassays

 

FL-Ng

FL-Ng

FL-Ng

Control (N = 26)

MCI-AD (N = 18)

AD (N = 23)

CT-Ng

rho = 0.815, P < 0.00001

rho = 0.279, N.S.

rho = 0.595, P = 0.003

SNAP-25

rho = 0.601, P = 0.001

rho = 0.329, N.S.

rho = 0.306, N.S.

Synaptotagmin, 215–223

rho = 0.642, P = 0.0004

rho = 0.340, N.S.

rho = 0.577, P = 0.004

Synaptotagmin, 238–245

rho = 0.640, P = 0.0004

rho = 0.344, N.S.

rho = 0.585, P = 0.003

 

CT-Ng

CT-Ng

CT-Ng

Control (N = 26)

MCI-AD (N = 18)

AD (N = 23)

FL-Ng

rho = 0.815, P < 0.00001

rho = 0.279, N.S.

rho = 0.595, P = 0.003

SNAP-25

rho = 0.736, P = 0.00002

rho = 0.458, N.S.

rho = 0.636, P = 0.001

Synaptotagmin, 215–223

rho = 0.815, P < 0.00001

rho = 0.512, P = 0.04

rho = 0.677, P = 0.0004

Synaptotagmin, 238–245

rho = 0.805, P < 0.00001

rho = 527, P = 0.03

rho = 0.702, P = 0.0002

  1. aCorrelations presented by Spearman’s rank correlation coefficient (rho). Non-significant (N.S.) correlation coefficients (P > 0.05)