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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Trichostatin A ameliorates Alzheimer’s disease-related pathology and cognitive deficits by increasing albumin expression and Aβ clearance in APP/PS1 mice

Fig. 5

TSA structurally and functionally promoted the phagocytosis of Aβ by BV2 cells. a Representative images of BV2 microglia in the different treatment groups. Scale bar, 10 μm. b Quantification of each morphological type of BV2 cells in the different treatment groups. n = 3 per group. c Representative images of microglia in APP/PS1 mice treated with vehicle or TSA. Scale bar, 10 μm. d Western blots and eg quantitative analysis for albumin, Ac-H4 and Aβ oligomers in BV2 cells. n = 3–5 per group. *p < 0.05, **p < 0.01, and ***p < 0.001

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