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Table 2 Gray matter volume reductions in amnestic mild cognitive impairment, compared to age-matched normal controls

From: Differences between memory encoding and retrieval failure in mild cognitive impairment: results from quantitative electroencephalography and magnetic resonance volumetry

 

x, y, z coordinate

Label

Cluster level

Peak level

p (FWE-corr)

equivk

p (FWE-corr)

T

equivZ

Amnestic MCI

21

− 21

12

Thalamus Lt

< 0.001

2324

< 0.001

7.84

7.34

− 12

− 41

6

Precuneus Lt

  

< 0.001

5.75

5.54

− 30

− 21

− 23

Parahippocampus Lt

  

0.001

5.62

5.42

53

0

− 11

Temporal Sup Rt

< 0.001

1573

< 0.001

5.70

5.49

60

− 21

− 14

Temporal Mid Rt

  

0.001

5.48

5.30

51

− 9

− 23

Temporal Mid Rt

  

0.002

5.37

5.19

12

20

32

Cingulum Mid Rt

< 0.001

567

< 0.001

5.68

5.47

12

30

33

Cingulum Mid Rt

  

0.003

5.23

5.07

14

33

24

Cingulum Mid Rt

  

0.006

5.09

4.94

− 29

21

42

Frontal Mid Lt

 

371

< 0.001

5.66

5.46

− 29

33

33

Frontal Sup Lt

  

0.001

5.45

5.26

− 36

21

33

Frontal Mid Lt

  

0.009

4.99

4.85

36

33

24

Frontal Mid Rt

 

241

0.001

5.63

5.4

29

27

38

Frontal Mid Rt

  

0.003

5.23

5.06

− 45

9

− 24

Temporal Pole Sup Lt

 

433

0.001

5.53

5.34

− 27

− 3

48

Precentral Lt

 

166

0.001

5.47

5.28

12

51

32

Frontal Sup Medial Rt

 

328

0.001

5.41

5.23

18

41

35

Frontal Sup Rt

  

0.002

5.38

5.20

23

51

23

Frontal Sup Rt

  

0.003

5.24

5.07

33

− 23

− 20

Parahippocampus Rt

 

621

0.002

5.32

5.15

30

− 5

− 30

Parahippocampus Rt

  

0.004

5.19

5.03

27

− 32

− 3

Hippocampus Rt

 

225

0.004

5.15

5.00

Encoding failure

− 20

− 20

14

Thalamus Lt

< 0.001

2926

< 0.001

6.7

6.25

− 12

− 38

6

Hippocampus Lt

  

< 0.001

6.59

6.15

− 26

− 23

− 9

Hippocampus Lt

  

< 0.001

6.34

5.95

26

− 33

− 3

Hippocampus Rt

< 0.001

879

< 0.001

6.32

5.93

29

− 26

− 8

Hippocampus Rt

  

< 0.001

6.12

5.76

32

− 23

− 17

Hippocampus Rt

  

< 0.001

5.79

5.49

30

− 5

− 30

Parahippocampus Rt

0.002

160

< 0.001

6.02

5.68

Retrieval failure

− 21

− 23

9

Thalamus Lt

0.001

201

0

6.61

6.14

17

11

59

Frontal Sup Rt

0.002

174

0

5.86

5.53

51

0

− 11

Temporal Sup Rt

< 0.001

390

0.002

5.53

5.24

44

− 17

− 9

Temporal Sup Rt

  

0.003

5.41

5.14

44

− 3

− 18

Temporal Sup Rt

  

0.018

4.92

4.71

11

26

36

Cingulum Mid Rt

0.004

111

0.005

5.25

5

  1. FWE, p < 0.05. Local maximum more than 8.0 mm apart. MCI mild cognitive impairment, FWE family-wise error, Rt right, Lt left, Sup superior, Mid middle