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Table 4 Adjusted odds ratio in 5-year cognitive change across ATP-III lipid categories at baseline, OR (95%CI)

From: Sex-specific associations between lipids and cognitive decline in the middle-aged and elderly: a cohort study of Chinese adults

 

Global cognition†

Mental status†

Episodic memory†

Male

Female

 

Male

Female

 

Male

Female

Total cholesterol (mg/dl)

 < 200

ref

ref

ref

ref

ref

ref

 200~239

1.011 (0.848, 1.206)

1.010 (0.833, 1.226)

1.179 (0.983, 1.414)

1.175 (0.972, 1.421)

1.035 (0.869, 1.233)

0.914 (0.752, 1.111)

 240+

1.051 (0.807, 1.369)

1.242 (0.965, 1.600)

0.889 (0.681, 1.162)

1.295 (1.002, 1.675) b

1.040 (0.780, 1.387)

1.014 (0.791, 1.300)

LDL-c (mg/dl)

 < 100

ref

ref

ref

Ref

ref

ref

 100~129

0.979 (0.813, 1.178)

1.308 (1.051, 1.627) b

0.996 (0.827, 1.199)

1.302 (1.047, 1.618) b

1.004 (0.835, 1.207)

1.207 (0.973, 1.496)

 130~159

0.918 (0.727, 1.160)

1.291 (1.017, 1.639) b

0.984 (0.776, 1.248)

1.357 (1.071, 1.720) a

0.943 (0.748, 1.189)

1.058 (0.828, 1.351)

 160~189

0.976 (0.696, 1.367)

1.377 (1.002, 1.891) b

0.873 (0.611, 1.249)

1.491 (1.076, 2.066) b

1.134 (0.790, 1.629)

1.120 (0.819, 1.531)

 190+

0.998 (0.644, 1.546)

1.424 (0.933, 2.172)

0.807 (0.505, 1.289)

1.283 (0.838, 1.967)

1.283 (0.802, 2.054)

0.903 (0.576, 1.415)

HDL-c (mg/dl)

 < 40

ref

ref

ref

ref

ref

ref

 40~59

0.822 (0.679, 0.994) a

1.159 (0.928, 1.447)

0.808 (0.665, 0.980) b

1.161 (0.933, 1.443)

0.861 (0.711, 1.042)

1.087 (0.873, 1.354)

 60+

0.794 (0.629, 1.001)

1.294 (1.002, 1.671) b

0.769 (0.614, 0.964) b

1.246 (0.967, 1.606)

0.898 (0.711, 1.134)

1.245 (0.966, 1.605)

Triglycerides (mg/dl)

 < 150

ref

ref

ref

ref

ref

ref

 150~199

0.981 (0.766, 1.257)

1.015 (0.795, 1.296)

1.008 (0.781, 1.302)

1.184 (0.938, 1.494)

0.870 (0.675, 1.120)

0.800 (0.630, 1.015)

 200+

1.088 (0.863, 1.371)

0.836 (0.663, 1.054)

1.097 (0.864, 1.394)

0.955 (0.760, 1.200)

1.043 (0.819, 1.329)

0.804 (0.628, 1.031)

  1. OR odds ratio, CI confidence interval, LDL-c low-density lipoprotein cholesterol, HDL-c high-density lipoprotein cholesterol
  2. †Adjusted for baseline age, education, marital status, registered residence, body mass index, alcohol use, smoking status, diabetes, hypertension, social activity, health insurance status, and lipid-lowering medication use
  3. aP < 0.05 after the Bonferroni correction
  4. bP < 0.05 before the Bonferroni correction
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Alzheimer's Research & Therapy

ISSN: 1758-9193