Skip to main content

Table 3 Multivariate analysis of perfusion density of large vessels and foveal avascular zone with cognitive impairment

From: Retinal microvasculature dysfunction is associated with Alzheimer’s disease and mild cognitive impairment

Cognitive status

Superficial capillary plexus

Deep capillary plexus

Mean ± SD

β

95 CI

P value*

Mean ± SD

β

95 CI

P value*

Perfusion density of large vessels (%)

 Control

6.92 ± 1.16

Reference

 

 

 MCI

6.39 ± 1.27

− 0.53

− 1.15 to 0.09

0.091

 AD

7.02 ± 1.29

0.10

− 0.61 to 0.81

0.787

Foveal avascular zone area (mm2)

 Control

0.31 ± 0.12

Reference

1.11 ± 0.47

Reference

 MCI

0.35 ± 0.12

0.041

− 0.02 to 0.10

0.190

1.24 ± 0.39

0.129

− 0.07 to 0.33

0.197

 AD

0.34 ± 0.14

0.034

− 0.04 to 0.11

0.380

1.13 ± 0.43

0.016

− 0.23 to 0.26

0.898

  1. AD Alzheimer’s disease, CI confidence intervals, MCI mild cognitive impairment, SD standard deviation
  2. *Adjusted for age, gender, race, diabetes, blood pressure (systolic and diastolic levels), and signal strength of OCTA scans