Table 1 Characteristics of participants by cognitive status
Characteristics | AD (n = 24) | MCI (n = 37) | Control (n = 29) | P value* |
|---|---|---|---|---|
Age | 74.9 ± 6.0 | 77.9 ± 6.4 | 76.7 ± 5.3 | 0.176 |
Gender, female | 17 (73) | 16 (44) | 13 (45) | 0.082 |
Race, Chinese | 16 (84) | 30 (82) | 23 (79) | 0.082 |
Diabetes, yes | 9 (41) | 10 (32) | 4 (14) | 0.039 |
Hypertension, yes | 15 (78) | 21 (62) | 17 (59) | 0.319 |
Systolic blood pressure, mmHg | 148 ± 11 | 139 ± 18 | 131 ± 16 | 0.008 |
Diastolic blood pressure, mmHg | 73 ± 9 | 70 ± 9 | 70 ± 8 | 0.363 |
MMSE | 20.3 ± 6.1 | 23.9 ± 6.3 | 24.8 ± 4.8 | 0.026 |
Neuroimaging markers | ||||
MTA scores | 1.3 ± 0.7 | 1.4 ± 0.8 | 1.7 ± 0.7 | 0.297 |
GCA scores | 1.5 ± 0.6 | 1.6 ± 0.6 | 2.3 ± 0.8 | 0.006 |
WMH scores | 1.6 ± 0.7 | 1.5 ± 0.7 | 2.1 ± 0.7 | 0.098 |
Signal strength, out of 10 | 9.8 ± 0.8 | 9.8 ± 0.5 | 9.6 ± 0.7 | 0.010 |