Table 1 Baseline demographic characteristics of 272 participants who completed the baseline study

N

195

77

134

24

61

53

Baseline age (years)

70.4 ± 10.3

70.0 ± 8.6

68.4 ± 10.3

65.5 ± 8.3

74.7 ± 8.7

72.1 ± 7.9

Females (%)

127 (65%)

51 (66%)

90 (67%)

16 (67%)

37 (61%)

35 (66%)

Education (years)

11.1 ± 4.9

11.2 ± 5.0

11.0 ± 4.9

11.4 ± 4.2

11.2 ± 4.8

11.1 ± 5.3

Duration (years)

2.6 ± 1.5

3.1 ± 1.4

2.3 ± 1.5

2.4 ± 1.3

3.0 ± 1.5

3.2 ± 1.4

Aβ-positivity (%)

61 (31%)

53 (69%)^a

0 (0%)

0 (0%)

61 (100%)

53 (100%)

ε2/2:ε2/3:ε3/3

1:37:157

n.a.

1:31:102

n.a.

0:6:55

n.a.

ε2/4:ε3/4:ε4/4

n.a.

2:60:15

n.a.

2:21:1

n.a.

0:39:14

Baseline diagnosis, CU/MCI/DEM (%)

79/75/41 (41/38/21%)

17/30/30^a (22/39/39%)

72/49/13 (54/37/10%)

15/7/2 (63/29/8%)

7/26/28 (11/43/46%)

2/23/28 (4/43/53%)

MMSE

25.4 ± 4.7

23.5 ± 5.3^a

26.8 ± 3.2

26.7 ± 2.5

22.2 ± 5.7

22.1 ± 5.7

CDR-SB

1.6 ± 2.3

2.7 ± 2.5^a

0.9 ± 1.5

0.8 ± 1.4

3.1 ± 3.0

3.6 ± 2.4