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Table 2 Neuropsychiatric symptoms in the whole DELCODE sample and per diagnostic group at baseline

From: Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers—results from the DELCODE study

 

Total

CO

SCD

MCI

AD

REL

n

M, SD

n

M, SD

n

M, SD

n

M, SD

n

M, SD

n

M, SD

Number of reported NPI-Q Items

665

1.3 (1.8)

203

0.4 (0.8)

228

1.4 (1.8)

113

2.2 (2.0)

77

2.6 (2.5)

44

0.9 (1.3)

GDS-15 total score

664

1.5 (1.8)

204

0.7 (1.3)

233

1.8 (1.8)

109

2.1 (1.9)

75

2.2 (1.8)

43

1.0 (1.5)

GAI-SF total score

686

1.0 (1.1)

209

0.7 (0.8)

241

1.2 (1.2)

115

1.0 (1.1)

77

1.1 (1.2)

44

1.2 (1.1)

 

n

%

n

%

n

%

n

%

n

%

n

%

NPS ≥ 1

334

50.2

53

26.1

122

53.5

83

73.5

56

72.7

20

45.5

NPS ≥ 2

218

32.8

23

11.3

70

30.7

68

60.2

48

62.3

9

20.5

GDS-15 score ≥ 1

427

64.3

74

36.3

177

76.0

91

83.5

62

82.7

23

53.5

GAI-SF score ≥ 1

401

58.5

103

49.3

157

65.1

65

56.5

46

59.7

30

68.2

  1. AD Alzheimer’s disease, GDS-15 Geriatric Depression Scale 15-item version, GAI-SF Geriatric Anxiety Inventory—Short Form, CO healthy controls, MCI mild cognitive impairment, NPI-Q Neuropsychiatric Inventory Questionnaire, NPS neuropsychiatric symptoms, REL first-degree relatives of AD patients, SCD subjective cognitive decline