Fig. 3From: Quantitative detection and staging of presymptomatic cognitive decline in familial Alzheimer’s disease: a retrospective cohort analysisData-driven preclinical cognitive decline in familial Alzheimer’s disease. Cumulative probability of preclinical abnormality as a function of years prior to estimated disease onset. A plateau means the data suggest that preclinical cognitive decline has stalled—it does not mean that the test score is at floor/ceiling. Progression sequence is that of the cross-validated event-based model in Fig. 1Back to article page