Groups | n | Estimated mean within-group change from baseline (95% CI) | Estimated mean between-group difference in change from baseline (95%CI) | |||
---|---|---|---|---|---|---|
Vs control | p | Adjusted p* | ||||
Primary analysis | ||||||
Effect of MI At 6 months | MI plus placebo or omega-3 | 34 | 0.008 (− 0.011; 0.027) | 0.004 (− 0.022; 0.030) | 0.752 | 0.901 |
No MI plus placebo or omega-3 | 33 | 0.004 (− 0.014; 0.022) | – | – | – | |
Secondary analysis | ||||||
Effect of MI at 12 months | MI plus placebo or omega-3 | 34 | 0.016 (− 0.022; 0.055) | 0.008 (− 0.044; 0.061) | 0.752 | 0.901 |
No MI plus placebo or omega-3 | 33 | 0.008 (− 0.027; 0.044) | – | – | – | |
Effect of omega-3 at 6 months | Omega-3 plus MI or no MI | 38 | 0.009 (− 0.009; 0.026) | 0.007 (− 0.019; 0.033) | 0.612 | 0.352 |
No omega-3 plus MI or no MI | 29 | 0.002 (−0.018; 0.022) | – | – | – | |
Effect of omega-3 at 12 months | Omega-3 plus MI or no MI | 38 | 0.018 (− 0.017; 0.052) | 0.013 (− 0.039; 0.066) | 0.612 | 0.352 |
No omega-3 plus MI or no MI | 29 | 0.004 (− 0.035; 0.043) | – | – | – | |
Exploratory analysis | ||||||
Effect of MI, omega-3, and combination of both at 6 months | MI plus omega-3 | 20 | 0.008 (− 0.017; 0.033) | 0.010 (− 0.026; 0.047) | 0.572 | 0.552 |
Omega-3 only | 18 | 0.009 (− 0.015; 0.033) | 0.012 (− 0.024; 0.047) | 0.524 | 0.236 | |
MI only | 14 | 0.008 (− 0.021; 0.038) | 0.010 (− 0.029; 0.050) | 0.603 | 0.637 | |
Placebo | 15 | − 0.002 (− 0.028; 0.024) | – | – | – | |
Effect of MI, omega-3, and combination of both at 12 months | MI plus omega-3 | 20 | 0.017 (− 0.034; 0.067) | 0.021 (− 0.052; 0.093) | 0.572 | 0.552 |
Omega-3 only | 18 | 0.019 (− 0.030; 0.067) | 0.023 (− 0.048; 0.094) | 0.524 | 0.236 | |
MI only | 14 | 0.017 (− 0.042; 0.075) | 0.021 (− 0.058; 0.100) | 0.603 | 0.637 | |
Placebo | 15 | − 0.004 (− 0.057; 0.048) | – | – | – |