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Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: Normalization of CSF pTau measurement by Aβ40 improves its performance as a biomarker of Alzheimer’s disease

Fig. 6

Associations between longitudinal cognitive decline and baseline Aβ PET, CSF pTau/Aβ40, and tau PET. Associations between annual PACC change (ΔPACC) and baseline a Aβ PET (Centiloid), b CSF pTau/Aβ40 ratio, c temporal tau PET (Temporal-metaROI FTP SUVR), and d entorhinal tau PET (entorhinal FTP SUVR). Abbreviations: Aβ = amyloid-β; AD = Alzheimer’s disease; CU = cognitively unimpaired; FTP = 18F-flortaucipir; MCI = mild cognitive impairment; PACC = Preclinical Alzheimer Cognitive Composite; pTau = phosphorylated tau; SUVR = standardized uptake value ratio

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Alzheimer's Research & Therapy

ISSN: 1758-9193