Fig. 7
From: Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration
Propagation of tau and atrophy. Representative brain sections with measures of hippocampus and cortex thickness as an indicator of atrophy in WT (a), tTA (b), Tg+DOX (c) and Tg (d) mice. Calculated average bilateral hippocampus and cortex thickness (e). An additional scoring scheme of tau propagation with PG-5-positive cell expression (brown) and NeuN (blue) in the hippocampus (f) with corresponding pathology score. Pathology scores for the hippocampus (g), lateral hypothalamus (h) and ventromedial hypothalamus (i). Asterisks (*) denote statistical significance (p < 0.05) between WT vs Tg, †WT vs Tg+DOX, ‡WT vs tTA, ¥Tg vs Tg+DOX, ¢Tg vs tTA and ¤Tg+DOX vs tTA