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Table 3 Effect of exercise under exposure to the 40-Hz light flickering on Akt/Tau in the hippocampus

From: Physical exercise during exposure to 40-Hz light flicker improves cognitive functions in the 3xTg mouse model of Alzheimer’s disease

Group

p-Akt/Akt ratio

P-GSK3β/GSK3β ratio

p-Tau/tau ratio

CON

1.00 ± 0.07

1.00 ± 0.13

1.00 ± 0.03

AD

0.57 ± 0.05*

0.48 ± 0.05*

2.15 ± 0.11*

AD+40

0.80 ± 0.15*#

0.75 ± 0.04*#

1.88 ± 0.09*#

AD+EX

0.84 ± 0.04*#

0.77 ± 0.05*#

1.70 ± 0.10*#

AD+40+EX

1.24 ± 0.04*#+

1.16 ± 0.07*#+

1.06 ± 0.04*#+

  1. *P < .05 compared to the CON group, #P < .05 compared to the AD group, +P < .05 compared to the AD+40 and AD+EX
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Alzheimer's Research & Therapy

ISSN: 1758-9193