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Table 1 Effect of exercise under exposure to the 40-Hz light flickering on spatial learning and memory and long-term memory

From: Physical exercise during exposure to 40-Hz light flicker improves cognitive functions in the 3xTg mouse model of Alzheimer’s disease

 

Spatial learning training (s)

SM (%)

LTM (s)

Group

1 day

2 days

3 days

4 days

5 days

CON

45.00 ± 3.76

24.20 ± 4.54

29.00 ± 3.71

17.07 ± 4.06

13.73 ± 2.54

33.57 ± 1.97

203.60 ± 23.73

AD

60.00 ± 0.0*

57.67 ± 1.17*

52.75 ± 3.71*

43.25 ± 3.88*

34.92 ± 5.78*

16.93 ± 2.31*

54.40 ± 16.90*

AD+40

51.93 ± 4.33

42.67 ± 4.40*

29.53 ± 5.34#

17.40 ± 3.37#

14.53 ± 3.63#

29.10 ± 1.42*#

161.20 ± 10.95*#

AD+EX

58.00 ± 2.05

54.05 ± 2.05*

31.08 ± 4.58#

19.08 ± 3.06#

15.50 ± 1.32#

31.08 ± 3.66*#

168.40 ± 24.86*#

AD+40+EX

52.56 ± 3.22

39.94 ± 4.87*

22.11 ± 3.48#

13.17 ± 3.38#

10.83 ± 2.22#

43.01 ± 2.05*#+

250.83 ± 28.29*#+

  1. *P < .05 compared to the CON group, #P < .05 compared to the AD group, +P < .05 compared to the AD+40 and AD+EX. SM spatial memory, LTM long-term memory