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Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse

Fig. 6

NJK14047 treatment from 6 to 9 months of age inhibits neuronal deaths in the cortex and hippocampus. a Representative confocal microscope images of mouse brain sections stained with Fluoro-Jade B dye for labeling degenerating neurons in the cortex and hippocampus (scale bar = 100 μm). b Quantitative analysis was performed with four sections in each mouse and four areas in each section. Fluoro-Jade B-positive cells per square millimeter were quantitated. Data are shown as mean ± SEM (n = 5 per group, one-way ANOVA). #P < 0.05 vs. wild type; *P < 0.05 vs. 5XFAD

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