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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer’s disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study

Fig. 3

a Box-whisker plots of percent change from baseline for CSF Aβ1–40 biomarker level by final dose groups at the end of month 6 of atabecestat treatment in ALZ2002 early AD population. b Percent change from baseline time profile for CSF Aβ1–40 levels to 52 weeks in ALZ2004 double-blind period. The line inside the box represents the median value, and the symbol represents the mean value. The outer box borders represent the lower and upper quartile (25th and 75th percentiles of the data)

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Alzheimer's Research & Therapy

ISSN: 1758-9193