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Table 3 Cognitive test results for each cohort

From: The age-related effect on cognitive performance in cognitively healthy elderly is mainly caused by underlying AD pathology or cerebrovascular lesions: implications for cutoffs regarding cognitive impairment

Cognitive test

A. Study cohort

B. No progress in CDR

C. No amyloid or tau pathology

D. No vascular pathology

E. No measurable in vivo pathology

ADAS-delayed recall

1.98 (1.93)

1.79 (1.72)

1.80 (1.78)

1.81 (1.80)

1.59 (1.56)

ADAS naming

0.38 (0.79)

0.34 (0.74)

0.36 (0.79)

0.30 (0.75)

0.24 (0.68)

Animal Fluency

21.7 (5.5)

22.1 (5.4)

22.0 (5.5)

22.4 (5.3)

23.0 (5.3)

AQT

66.0 (12.9)

65.1 (12.3)

65.8 (12.9)

63.8 (12.0)

63.3 (11.1)

Stroop

28.9 (7.4)

28.5 (7.0)

28.6 (7.5)

27.5 (6.9)

26.9 (6.7)

TMT A

46.0 (17.0)

45.6 (17.1)

45.6 (16.9)

43.0 (14.8)

41.0 (12.0)

TMT B

104.4 (50.8)

101.8 (49.4)

101.9 (49.0)

97.1 (44.7)

90.0 (36.5)

SDMT

37.0 (8.4)

37.5 (8.3)

37.5 (8.5)

38.4 (8.3)

39.1 (8.0)

  1. Data are shown as mean (SD). A: The entire population. B: No progress in Clinical Dementia Rating (CDR) over 2 years. C: No preclinical AD (i.e., CSF Aβ42/40 and P-tau not abnormal). D: No vascular pathology. E: No measurable pathology (i.e., no AD pathology, cerebrovascular pathology or increased NfL)