Table 4 Univariate logistic regression for enrolment and CSF Aβ1–42 positivity in whole sample and stratified by recruitment setting

Outcome

Enrolment^*

CSF Aβ +ve^{^}

Enrolment^*

CSF Aβ +ve^{^}

Enrolment^*

CSF Aβ +ve^{^}

Enrolment^*

CSF Aβ +ve^{^}

Enrolment^*

CSF Aβ +ve^{^}

Aged over 70 years Old

0.97 (0.95–0.99)

1.06 (1.02–1.10)

0.99 (0.94–1.03)

1.10 (1.01–1.20)

0.99 (0.95–1.03)

1.01 (0.94–1.08)

0.97 (0.93–1.01)

1.23 (1.08–1.45)

0.96 (0.93–1.00)

1.03 (0.97–1.11)

Male

1.56 (1.19–2.04)

1.28 (0.81–2.04)

1.17 (0.58–2.42)

0.30 (0.08–0.96)

2.03 (1.24–3.35)

2.03 (0.92–4.60)

1.81 (1.11–3.01)

1.35 (0.47–4.08)

1.13 (0.66–1.94)

2.01 (0.77–5.36)

Highly educated

1.64 (1.23–2.17)

0.89 (0.56–1.42)

1.44 (0.69–2.98)

0.72 (0.25–2.13)

1.42 (0.87–2.31)

1.10 (0.50–2.39)

2.20 (1.34–3.59)

0.66 (0.22–1.88)

1.33 (0.67–2.67)

0.75 (0.24–2.51)

APOE ɛ4 genotype

0.95 (0.70–1.28)

2.99 (1.81–4.94)

NA

6.42 (1.93–24.1)

0.68 (0.41–1.10)

1.72 (0.79–3.86)

1.37 (0.84–2.25)

7.20 (2.2–28.77)

0.92 (0.49–1.72)

3.34 (1.22–9.48)

Family history of Dementia

1.66 (1.19–2.31)

1.58 (0.83–3.00)

1.04 (0.50–2.15)

0.95 (0.31–2.98)

1.12 (0.38–3.23)

NA^#

2.95 (1.73–4.91)

2.90 (0.97–8.96)

1.27 (0.73–2.22)

1.94 (0.68–6.09)

Subjective cognitive decline

0.86 (0.58–1.27)

1.51 (0.88–2.61)

0.29 (0.09–0.76)

2.93 (0.67–20.6)

0.79 (0.41–1.55)

1.15 (0.38–3.22)

NA

NA

1.16 (0.62–2.15)

1.73 (0.62–4.79)

Low memory score

0.84 (0.60–1.17)

1.47 (0.82–2.61)

0.63 (0.21–1.87)

18.90 (2.87–377)

0.95 (0.56–1.64)

1.29 (0.55–2.96)

0.78 (0.44–1.31)

0.95 (0.28–3.02)

0.91 (0.29–2.83)

0.58 (0.03–4.98)