Fig. 5
From: Systemic and central nervous system metabolic alterations in Alzheimer’s disease
Associations of plasma (left) and CSF (right) metabolite concentrations with core AD pathology as measured by CSF biomarker concentrations. Results from linear regression analysis are presented; colors represent beta-coefficients of the CSF biomarker estimate (red for positive association, blue for negative association), circle size represents P value of the CSF biomarker estimate (P < 0.01 or P < 0.05, for large and small respectively). Figure depicts the results of linear metabolite concentration ~ CSF biomarker model that remained significant after the correction for age and gender. Detailed results for age- and gender-corrected models are given in Additional file 1: Table S7